The Guptas are suspected of using their ties with Jacob Zuma to change cupboard positions and land state contracts.
Elite officers from the Hawks entered the Gupta devalue in Saxondale, Johannesburg, on Wednesday.
Police described the area as a “crime scene”.
According to South African Broadcasting Corporation, 3 people were arrested this morning in operations at several addresses.
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Both the Guptas and Mr Zuma repudiate any wrongdoing.
Hawks orator Hangwani Mulaudzi pronounced the raid was partial of a examine into change peddling allegations and added: “We’re not personification around in terms of making certain that those who are obliged in the supposed state capture, they take shortcoming for it.”
He did not give sum of what was seized at the home.
As the raid was carried out, Tessa Turvey, conduct of the residents’ association, said: “Finally something is being finished about it. These guys must get out of the country. They must leave us alone. They have finished adequate damage.”
It comes after the statute party, the African National Congress, told Mr Zuma to renounce on Tuesday, following a series of scandals.
A legal elect will examine the purported crime compared with the Gupta brothers, who changed to South Africa from India in the 1990s.
Mr Zuma’s son Duduzane had a business attribute with the Guptas.
Mr Zuma has not nonetheless responded to his party’s proclamation that he must leave office, despite the ANC selecting his successor.
The party is desperately trying to solve the care predicament and rebound back in popularity, having suffered a drop when the scandals emerged.
South Africa’s arch prosecutor is approaching to make a decision on either Mr Zuma should face old charges of crime tied to an arms understanding two decades ago.
They were backed last year having been thrown out in 2009.
The country’s top justice also ruled in 2016 that Mr Zuma had disregarded the structure when he used state supports to compensate for multi-million dollar upgrades to his private home. He repaid some of the money.
The ANC is awaiting a matter from Mr Zuma today, but the president’s bureau denied there had been a communication of a special briefing.
Deputy President Cyril Ramaphosa is prepared to take over from Mr Zuma.