Both were in assemblage on Monday, with the paintings imprinting the first time African American artists have been consecrated to paint the central portraits.
New York painter Kehinde Wiley, famous for his naturalistic design depicting black people in drastic and jubilant poses, was tasked with Mr Obama’s portrait.
“I tried to negotiate reduction grey hairs, but Kehinde’s firmness would not concede him to do what we asked,” joked Mr Obama.
He described the portrait, which depicts him sitting on a wooden chair against a colourful, shaggy backdrop, as “extraordinary”, adding: “It’s my good honour to be here. It means so much to us.”
Mr Wiley, a Yale University graduate, took thousands of photographs of the 44th US boss in sequence to ideal the portrait, which will be on show in the America’s Presidents exhibition.
Baltimore artist Amy Sherald was consecrated to do Mrs Obama’s portrait, reduction than two years after she became the first to win the National Portrait Gallery’s Outwin Boochever Portrait Competition.
“I’m a little overwhelmed, shamed and proud,” pronounced Mrs Obama, who praised the mural as “amazing”.
Addressing Ms Sherald, Mr Obama added: “I wish to appreciate you for so spectacularly capturing the grace, and beauty, and intelligence, and charm… and hotness, of the lady that we love.
“I am in astonishment of Kehinde’s gifts, and what he and Amy have given to this country and to the world, and we are both very beholden to have been the concentration of their courtesy for this moment.”
Mrs Obama’s large-scale portrayal will also go on display at the gallery, which is partial of the Smithsonian Institution.
The gallery was packaged for the unveiling, with executive Steven Spielberg and actor Tom Hanks among the famous faces in the audience.